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- Researcher Hopes to Find More Accurate Alcohol-Use Test
Researcher Willard M. Freeman is working on a protein project that he hopes will lead to the creation of a simple, more accurate diagnostic test to measure alcohol usage than those now available, writes Chris Sholly of Lebanon Daily News.
- Proteins in Blood May Predict Levels of Alcohol Consumption
Measuring a set of protein changes in the blood linked to alcohol use may potentially lead to a more accurate diagnostic test than those currently available, according to Penn State College of Medicine researchers.
- New Data Revealed Regarding Criteria for Alcohol Use Disorders
New research finds that “the relative severity of the 11 DSM-IV alcohol use disorder (AUD) criteria are represented by their severity threshold scores, an item response theory (IRT) model parameter inversely proportional to their prevalence. These scores can be used to create a continuous severity measure comprising the total number of criteria endorsed, each weighted by its relative severity.” The study, titled “A multidimensional assessment of the validity and utility of alcohol use disorder severity as determined by item response theory models,” is published in Drug and Alcohol Dependence.
- Genes May Influence Alcoholism in Spanish American Males
Cytokines are small proteins secreted by cells that serve as molecular messengers between cells. Pro-inflammatory cytokines—which function in the immune system—may be involved in alcohol dependence (AD). Science Daily reports that a study of three polymorphisms of the interleukin-1 gene complex (IL-1) and one of the tumor necrosis factor-alpha (TNFα) has found that IL-1 may directly contribute to AD among Spanish Caucasian males.
